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Nano Scaffold Developed To Rebuild Nerve Damage 2008-05-03 02:15:00 A Monash University PhD student has developed a new technique that could revolutionise stem cell treatment for Parkinson's disease and spinal cord injury. David Nisbet from Monash University's Department of Materials Engineering has used existing polymer-based biodegradable fibres, 100 times smaller than a human hair, and re-engineered them to create a unique 3-D scaffold that could potentially allow stem cells to repair damaged nerves in the human body more quickly and effectively.Source: ScienceDaily, Feb. 2008 Read more:Nerve
, Damage
Electrospun zein fibers using glutaraldehyde as the cross-linking reagent-effect of time and temperature 2008-05-03 00:56:00 With the fast-growing bio-ethanol industry, it is very important to use the co-products generated during ethanol production in a fashion that will improve the economics of this new industry. Zein, the dominant corn protein, is present in large amounts in the main co-products of both wet-milling and dry-milling ethanol plants. It is typically isolated from corn gluten meal (generated by ethanol producers using wet milling techniques). The main use of zein historically was in the textile fibers market.Ref: S.Gordon, W.Kristen, S.David, B.Atanu, Macromolecular Chemistry and Physics, 2008 Read more:effect
Electrospun nanofibers: solving global issues 2008-05-03 00:06:00 Nanofibers are able to form a highly porous mesh and their large surface-to-volume ratio improves performance for many applications. Electrospinning has the unique ability to produce nanofibers of different materials in various fibrous assemblies. The relatively high production rate and simplicity of the setup makes electrospinning highly attractive to both academia and industry. A variety of nanofibers can be made for applications in energy storage, healthcare, biotechnology, environmental engineering, and defense and security.Ref: Materials Today, Volume 9, Issue 3, March 2006, Pages 40-50
Biomaterials for tendon repair 2008-05-02 21:18:00 Scientists at The University of Manchester, UK, are investigating the use of electrospun polycaprolactone nanofibres to regenerate damaged tendons. Because the bundle of fibres replicates the morphology of tendon tissue, researchers envisage that the synthetic structure will perform the mechanical function of the tendon while it repairs itself, as well as act as a temporary scaffold to promote cell migration and new tissue formation. Research will now focus on pre-clinical tests in the Achilles heal of a mouse, exploring control of biodegradation in terms of strength retention and mass loss.Source: Materials World
Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc. 2008-05-02 21:10:00 Organogenesis, Inc., the world's most successful regenerative medicine company, announced the strategic acquisition of Baton Rouge-based NanoMatrix, Inc. NanoMatrix's platform technology develops "designer scaffolds" for the purposes of regenerative medicine, based on the fabrication technique known as electrospinning.Source: Organogenesis Read more:Acquisition
Electrospun memories 2008-05-02 08:54:00 Far from being simple conductors for transporting charge in future nanoelectronic devices, nanowires exhibit unique characteristics that could be also be exploited for other applications. An example of such multifunctional properties is provided by Wei Pan and colleagues at Tsinghua University in Beijing, China who find that aluminium-doped zinc oxide (AZO) nanowires exhibit both photoconductivity and voltage–induced bistable switching behaviour.Ref: Lin, D., Wu, H. & Pan, W. Advanced Materials 19, 3968–3972 (2007) Read more:memories
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International Council on Nanotechnology Launches Global Research Needs Assessment 2008-05-05 00:03:00 Last year, more than 70 experts from 13 countries - in academia, industry, governments and non-governmental agencies - accepted that challenge. In an unprecedented international collaboration, the InternationalCouncil
on Nanotechnology
(ICON) convened two workshops aimed at defining a set of research needs for assessing potential nanotechnology impacts. The results of this multi-stakeholder effort, funded by ICON and the National Science Foundation, will be unveiled on Thursday, May 1, when ICON, in partnership with the Project on Emerging Nanotechnologies, releases the “International Assessment
of Nanotechnology Environment, Health and Safety ResearchNeeds
” - a report on the findings of the two workshops.Source: Project on Emerging Nanotechnologies Read more:Global
Nano Scaffold Developed To Rebuild Nerve Damage 2008-05-03 02:15:00 A Monash University PhD student has developed a new technique that could revolutionise stem cell treatment for Parkinson's disease and spinal cord injury. David Nisbet from Monash University's Department of Materials Engineering has used existing polymer-based biodegradable fibres, 100 times smaller than a human hair, and re-engineered them to create a unique 3-D scaffold that could potentially allow stem cells to repair damaged nerves in the human body more quickly and effectively.Source: ScienceDaily, Feb. 2008 Read more:Nerve
, Damage
Electrospun zein fibers using glutaraldehyde as the cross-linking reagent-effect of time and temperature 2008-05-03 00:56:00 With the fast-growing bio-ethanol industry, it is very important to use the co-products generated during ethanol production in a fashion that will improve the economics of this new industry. Zein, the dominant corn protein, is present in large amounts in the main co-products of both wet-milling and dry-milling ethanol plants. It is typically isolated from corn gluten meal (generated by ethanol producers using wet milling techniques). The main use of zein historically was in the textile fibers market.Ref: S.Gordon, W.Kristen, S.David, B.Atanu, Macromolecular Chemistry and Physics, 2008 Read more:effect
Electrospun nanofibers: solving global issues 2008-05-03 00:06:00 Nanofibers are able to form a highly porous mesh and their large surface-to-volume ratio improves performance for many applications. Electrospinning has the unique ability to produce nanofibers of different materials in various fibrous assemblies. The relatively high production rate and simplicity of the setup makes electrospinning highly attractive to both academia and industry. A variety of nanofibers can be made for applications in energy storage, healthcare, biotechnology, environmental engineering, and defense and security.Ref: Materials Today, Volume 9, Issue 3, March 2006, Pages 40-50
Biomaterials for tendon repair 2008-05-02 21:18:00 Scientists at The University of Manchester, UK, are investigating the use of electrospun polycaprolactone nanofibres to regenerate damaged tendons. Because the bundle of fibres replicates the morphology of tendon tissue, researchers envisage that the synthetic structure will perform the mechanical function of the tendon while it repairs itself, as well as act as a temporary scaffold to promote cell migration and new tissue formation. Research will now focus on pre-clinical tests in the Achilles heal of a mouse, exploring control of biodegradation in terms of strength retention and mass loss.Source: Materials World
Organogenesis, Inc. Announces Acquisition of NanoMatrix, Inc. 2008-05-02 21:10:00 Organogenesis, Inc., the world's most successful regenerative medicine company, announced the strategic acquisition of Baton Rouge-based NanoMatrix, Inc. NanoMatrix's platform technology develops "designer scaffolds" for the purposes of regenerative medicine, based on the fabrication technique known as electrospinning.Source: Organogenesis Read more:Acquisition
Electrospun memories 2008-05-02 08:54:00 Far from being simple conductors for transporting charge in future nanoelectronic devices, nanowires exhibit unique characteristics that could be also be exploited for other applications. An example of such multifunctional properties is provided by Wei Pan and colleagues at Tsinghua University in Beijing, China who find that aluminium-doped zinc oxide (AZO) nanowires exhibit both photoconductivity and voltage–induced bistable switching behaviour.Ref: Lin, D., Wu, H. & Pan, W. Advanced Materials 19, 3968–3972 (2007) Read more:memories
Nano-engineering biocompatible materials 2008-05-06 07:33:00 A research team from the University of Manchester aims to develop a 3D scaffold appropriate for surgical implantation into damaged tendons. Highly aligned fibres to encourage correct formation of new muscle tissue and formation of 3D aligned fibrous bundles for tendon regeneration by using electrospinning. They envisage that this synthetic structure will perform the mechanical functions of a tendon whilst promoting cell migration and subsequent repair. Depending on the success of this, further clinical trials are planned and it is anticipated that an "off-the-shelf" product will be available within five years.Source: nanotechweb.org Read more:engineering
Feynman Prizes in Nanotechnology: Nominations due May 31 2008-05-05 23:18:00 The Foresight Institute Feynman Prizes
, named in honor of pioneer physicist Richard Feynman, are given in two categories, one for experiment and the other for theory in nanotechnology. Established in 1993, the prizes honor researchers whose recent work has most advanced the achievement of Feynman's goal for nanotechnology: the construction of atomically-precise products through the use of productive nanosystems."The Feynman Prizes have recognized the most important nanoresearch work for over a decade. We invite the nanotech community to let us know who most deserves to join this group of brilliant achievers," said Christine Peterson, President of Foresight Nanotech Institute.Nominations for the Feynman Prizes may be made at: www.foresight.org/prizeSource: Foresight Nanotech Institute Read more:Nanotechnology
Researchers produce 3-D nanotube circuits 2008-05-05 22:59:00 A team of researchers at the National Institute of Advanced Industrial Science and Technology in Tsukuba, Ibaraki Prefecture, has succeeded in producing hyperfine 3-D circuits using carbon nanotube
s, it was learned Sunday. The team led by Kenji Hata released their findings in the on-line version of the May 4 issue of Nature Nanotechnology. The discovery is expected to help reduce the size of integrated circuits and allow the development of highly sophisticated sensors, the researchers said. The researchers synthesized nanotubes by blowing carbon gas that had been heated to about 800 C over a silicon board. They then processed the resulting nanotubes applying a technique normally used to make semiconductors. The process enabled the researchers to produce
ultrafine wires as thin as 0.00
New Nanomaterial Doubles CO2 Storage 2008-05-08 02:52:00 As much as we reduce our current output of CO2 and other greenhouse gases into the atmosphere, it has become apparent that these efforts, while absolutely needed, will only mitigate the effects of global warming, making carbon sequestration as necessary tool in our fight against climate change.Unfortunately, many popular ideas on how exactly to sequester the CO2 are simply not practical, though some new ones are quite promising. A new team of French researchers, led by Gérard Férey at the University of Versailles, have decided to skip the pumping of CO2 underground, and focus their efforts on nanotechnology, breaking a record in the process. Their new material, dubbed MIL-101, has been officially called “the best carbon sequestration material” bar none. 1m3 is capable of holding 400m Read more:Doubles
Recent Patents on Electrospun Biomedical Nanostructures 2008-05-07 21:29:00 A SciFinder Scholar research survey conducted using different keywords such as “electrostatic or electrospinning and nanofiber” shows an increasing interest in nanofiber fabrication and related applications over the period of 9 years. In the year 2007 from January to November total 1728 publications related to nanofibers appeared which included 445 general patents and 117 biomedical application related patents. Similar trend continues with a refined search for total granted patents and nanofiber based biomedical applications. The disclosures that use nanofiber matrices can be broadly classified into different categories such as nanofibers for therapeutic agent delivery applications, as scaffolds for tissue engineering and for prosthetic applications.Ref: RecentPatents
on Biomedical
En
Continuous hollow alumina gel fibers by direct electrospinning of an alkoxide-based precursor 2008-05-09 01:07:00 Scientists from University of Florida, explored the nature and introduce the processing development of the sol–gel based fibers through electrospinning. The study contains the electrospinning of ceramic fibers of hydrous alumina directly from alkoxide-based precursors. The continuous fibrous bundles are produced with consistent tubular structures. The stability of the drawn fibers is dominated by the hydrolysis and condensation kinetics of the sol–gel precursor, which in parallel changes the processing parameter relationships found in traditional electrospinning.Ref: Chemical Engineering Journal, 137(1), March 2008, 137-143, Porous Inor. Mater. for Biomedical App.
Biodegradable microfiber implants delivering paclitaxel for post-surgical chemotherapy against malignant glioma 2008-05-08 21:34:00 Researchers from National University of Singapore developed paclitaxel-loaded biodegradable implants in the form of microfiber discs and sheets by using electrospinning technique and investigated against
malignant glioma in vitro and in vivo. They found that fibrous matrices not only provide greater surface area to volume ratio for effective drug release rates but also give the much needed implantability into tumor resected cavity in post-surgical glioma chemotherapy
.Ref: Biomaterials, Volume 29, Issue 20, July 2008, Pages 2996-3003 Read more:delivering
BioMimic fabrication of electrospun nanofibers with high-throughput 2008-05-08 21:26:00 Spider-spun fiber is of extraordinary strength and toughness comparable to those of electrospun fiber, the later needs a very high voltage (from several thousands voltage to several ten thousands voltages) applied to water-soluble protein “soup” that was produced by a spider, furthermore, its mechanical strength dramatically decreases comparable to spider silk. A possible mechanism in spider-spinning process is given, the distinct character in spider-spinning is that its spinneret consists of millions of nano scale tubes, and a bubble can be produced at the apex of each nano-tube. The surface tension of each bubble is extremely small such that it can be spun into nanofibers with an awfully small force, either by the spider’s body weight or tension created by the rear legs. We mimic t
Elmarco has won further recognition for its products in Switzerland 2008-05-10 02:34:00 The Liberec company Elmarco, which has gradually made a name for itself as a world producer of nanofibres and technologies for their mass production and usage, has recently earned further prestigious recognition on the international field. At INDEX 08, amid very keen competition from six hundred world exhibitors, producers of nonwoven materials from all over the world, Elmarco won two nominations for their “contribution to innovation” and “technological development” in the production of materials for the third millennium. Elmarco was the only exhibitor nominated twice.Source: Elmarco.com Read more:Switzerland
Spin control: New technique sorts nanotubes by length 2008-05-13 22:12:00 Researchers at the National Institute of Standards and Technology (NIST) have reported a new technique to sort batches of carbon nanotubes by length using high-speed centrifuges. Many potential applications for carbon nanotubes depend on the lengths of these microscopic cylinders, and one of the most important features of the new technique, say the scientists, is that it should be easily scalable
Nanobiotechnology Applications, Markets and Companies 2008-05-12 18:51:00 Nanotechnology is the creation and utilization of materials, devices, and systems through the control of matter on the nanometer-length scale (a nanometer is one billionth of a meter. Nanobiotechnology, an integration of physical sciences, molecular engineering, biology, chemistry and biotechnology holds considerable promise of advances in pharmaceuticals and healthcare. The report starts with an Read more:Applications
, Markets
, Companies
Molecular Orientation in Individual Electrospun Nanofibers Measured via Polarized Raman Spectroscopy 2008-05-16 19:02:00 Researchers from Cornell University present quantitative measurements of molecular orientation in a single nanofiber and compare these to the film samples. Such measurements could yield information about the uniformity of the electrospinning process and resulting fibers, and may also allow comparison between spectrally measured orientation functions and single fiber mechanical properties.Ref: doi: Read more:Molecular
, Individual
Towards control of smooth muscle cell differentiation in synthetic 3D scaffolds 2008-05-16 03:04:00 A central tenant of tissue engineering is that cells should be able to recapitulate full functional tissue capability when placed within an appropriate architecture or scaffold. The aim of this study was to examine the effect of three-dimensional (3D) architecture on the differentiated phenotype of human smoothmuscle
cells derived from the stroma of the lower urinary tract. Stromal cell cultures
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