Owner: Advair | Dutasteride | Finasteride URL:http://reneehamptonmedia.com/ Join Date: Sat, 15 Sep 2007 15:24:58 -0500 Rating:0 Site Description: Fluticasone asthma treatment, Avodart prostatic hyperplasia treatment, Hair Loss and prostatic treatment with Finasteride Site statistics:Click here
Actavis Launches Finasteride 5mg Tablets In The U.S 2007-09-15 20:23:36 Actavis Group (OMX: ACT), the international generic pharmaceuticals company, announced that it has received approval from the U.S. Food & Drug Administration to market Finasteride Tablets
, USP 5 mg. Distribution of the product will begin immediately.
Finasteride 5mg tablets are the generic equivalent of Merck & Company’s Proscar(R) tablets, which are indicated for the treatment of benign prostatic hypertrophy (BPH).
Annual sales of Finasteride 5mg tablets in the U.S. were approximately US$364 million for the twelve months ending March 2007 according to IMS Health data.
Doug Boothe, Executive VP of US Commercial & Administration, said, “The launch of finasteride tablets in the United States exemplifies the synergy generated from Actavis’ global R&D, sourcing and manufacturing network, and represents an important addition to our rapidly expanding product portfolio.”
About Actavis
Actavis is one of the world’s leading generic pha
Avodart Dutasteride Side Effects 2007-09-15 20:19:02
Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trial of another drug and may not reflect the rates observed in practice. The adverse reaction information from clinical trials does, however, provide a basis for identifying the adverse events that appear to be related to drug use and for approximating rates.
Most adverse reactions were mild or moderate and generally resolved while on treatment in both the AVODART and placebo groups. The most common adverse events leading to withdrawal in both treatment groups were associated with the reproductive system.
Over 4,300 male subjects with BPH were randomly assigned to receive placebo or 0.5-mg daily doses of AVODART in 3 identical 2-year, placebo-controlled, double-blind, Phase 3 treatment studies, each with 2-year open-label extensions. During the double-blind treatment period, 2,167 male subjects wer Read more:Effects
, Side Effects
Enlarged Prostate Drug Dutasteride Allows for Less Invasive Prostate Biopsies 2007-09-15 20:17:35 A drug that is currently used to treat an enlarged prostate may improve the accuracy of prostate biopsies, a pilot study shows.
The drug, dutasteride, suppresses blood flow in benign tissue of the prostate, allowing radiologists to better target cancer tissue using Doppler ultrasound, said Elizabeth Ives, MD, a research fellow at Thomas Jefferson University Hospital in Philadelphia and lead author of the study. The study included 11 patients who took dutasteride before their Doppler ultrasound-guided prostate biopsy. Based on blood flow reduction, biopsy was performed on one patient after one week of taking the drug, eight patients after two weeks of taking the drug and two patients after three weeks of taking the drug. Up to four targeted biopsies as well as six standard biopsies were performed on each patient. Prostate
cancer was detected in four of the patients using the targeted biopsy method; the standard method detected three of the four cancers, Dr. Ives said. “If Read more:Invasive
Sustained improvements in BPH symptoms with Avodart (dutasteride) new stud 2007-09-15 20:15:53 New four-year study demonstrates significant and sustained improvements in BPH symptoms
with Avodar (dutasteride)
– Data published in the April 2004 issue of Urology supports long-term use of Avodart in men with symptomatic BPH and an enlarged prostate –
New clinical study findings showed that men with symptoms of benign prostatic hyperplasia (BPH), also known as enlarged prostate, taking Avodart for four years had sustained, long-term improvement in three major markers of BPH — urinary symptoms, urinary flow rates and prostate volume reduction. Avodart is the first and only dual 5alpha-reductase (5AR) inhibitor approved for the treatment of BPH.
The new data, published in the April 2004 issue of Urology, are the pooled results from two recent US phase III multi-center, randomized, placebo-controlled trials of two year duration with a two year open-label extension.
Men taking Avodart for all four years experienced a significant improvement in urinary symptoms (mean of
Dutasteride Therapy Does Not Interfere With Clinical Usefulness Of Serum PSA For Detection Of Prostate Cancer 2007-09-15 20:15:01 UroToday.com - Dutasteride is a dual 5a-reductase inhibitor (5ARI) used in the treatment of BPH. Both dutasteride and a related drug, finasteride inhibit the transcription of PSA by decreasing the conversion of testosterone to dihydrotestosterone. It is known that doubling the serum PSA in patients taking finasteride provides an accurate determination of their PSA level. Dr. Andriole and colleagues report a similar finding for dutasteride in the May 2006 issue of the Journal of Urology.
A total of 2,802 men with BPH, no evidence of prostate cancer (CaP), a serum PSA level of 1.5-10ng/ml, a prostate volume >30cc, an AUA symptom score >12, and peak urinary flow rate 4ng/ml after doubling the measured PSA level to account for the effect of dutasteride.
Men taking placebo had an expected increase in PSA, reported as an 8.3% increase at the 24 month mark. The dutasteride treated men had a 60% reduction in their PSA, after doubling to correct for treatment.
The incidence of CaP was 3.3% and Read more:Cancer
, Detection
, Prostate
, Serum
, Therapy
, Usefulness
Dutasteride Induces Apoptosis In Androgen Sensitive Prostate Cancer Cell Lines 2007-09-15 20:14:05 UroToday.com - Dr. McCrohan as research colleagues from University College Dublin report that the dual 5 a-reductase inhibitor dutasteride induces apoptosis in androgen sensitive, but not androgen insensitive prostate cancer (CaP) cell lines and primary cultures. Their work appears in the epub version of Cancer
.
The administration of dutasteride (0.1-10mM) resulted in apoptosis in androgen sensitive LNCaP, pwR-1E, PNT-2 and PC3 (AR) cells. Apoptosis was assessed by quantification of cells with hypodiploid DNA by propidium iodide incorporation. LNCaP and PC3 (AR) cells remained responsive to treatment to 4 and 5 days, respectively. Androgen insensitive PC3 cells did not respond to dutasteride.
In first passage CaP primary cultures, dutasteride induced apoptosis in 7 samples, but not in 9 samples. The difference could not be explained by differences in dutasteride on cell cycle progression or expression of 5 a-reductase isoforms.
The Reduction by Dutasteride of Prostate
Cancer Events stu Read more:Lines
, Sensitive
Dutasteride Metabolism and Elimination 2007-09-15 20:12:58 Dutasteride is extensively metabolized in humans. In vitro studies showed that dutasteride is metabolized by the CYP3A4 and CYP3A5 isoenzymes. Both of these isoen-zymes produced the 4′-hydroxydutasteride, 6-hydroxydutasteride, and the 6,4′-dihydroxydutasteride metabolites. In addition, the 15-hydroxydutasteride metabolite was formed by CYP3A4. Dutasteride is not metabolized in vitro by human cytochrome P450 isoenzymes CYP1A2, CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP2E1. In human serum following dosing to steady state, unchanged dutasteride, 3 major metabolites (4′-hydroxydutasteride, 1,2-dihydrodutasteride, and 6-hydroxydutasteride), and 2 minor metabolites (6,4′-dihydroxydutasteride and 15-hydroxydutasteride), as assessed by mass spectrometric response, have been detected. The absolute stereochemistry of the hydroxyl additions in the 6 and 15 positions is not known. In vitro, the 4′-hydroxydutasteride and 1,2-dihydrodutasteride metabolites Read more:Elimination
, Metabolism
Dutasteride Absorption 2007-09-15 20:11:57 Following administration of a single 0.5-mg dose of a soft gelatin capsule, time to peak serum concentrations (Tmax) of dutasteride occurs within 2 to 3 hours. Absolute bioavail-ability in 5 healthy subjects is approximately 60% (range, 40% to 94%). When the drug is administered with food, the maximum serum concentrations were reduced by 10% to 15%. This reduction is of no clinical significance.Distribution: Pharmacokinetic data following single and repeat oral doses show that dutasteride has a large volume of distribution (300 to 500L). Dutasteride is highly bound to plasma albumin (99.0%) and alpha-1 acid glycoprotein (96.6%).
In a study of healthy subjects (n = 26) receiving dutasteride 0.5 mg/day for 12 months, semen dutast-eride concentrations averaged 3.4 ng/mL (range, 0.4 to 14 ng/mL) at 12 months and, similar to serum, achieved steady-state concentrations at 6 months. On average, at 12 months 11.5% of serum dutast-eride concentrations partitioned into semen.
Read more:Absorption
Dutasteride Other Effects 2007-09-15 20:10:35 Plasma lipid panel and bone mineral density were evaluated following 52weeks of dutast-eride 0.5mg once daily in healthy volunteers. There was no change in bone mineral density as measured by dual energy x-ray absorptiometry (DEXA) compared with either placebo or baseline. In addition, the plasma lipid profile (i.e., total cholesterol, low density lipoproteins, high density lipoproteins, and triglycerides) was unaffected by dutasteride. No clinically significant changes in adrenal hormone responses to ACTH stimulation were observed in a subset population (n = 13) of the 1-year healthy volunteer study.
Read more:Effects
Dutasteride: The latest research on male hair loss 2007-09-24 13:32:45 Male pattern baldness is the most common type of hair loss in men. Male hair loss is caused by increased sensitivity to androgens or male sex hormones in certain parts of scalp, and is mainly a genetic problem.
In the past, baldness was seen as undesirable or unfortunate. Nowadays it is a serious problem; so first we should seek for a hair loss solution and then think of other related medical treatment.
Baldness is a major problem in both men and women. Young men with frontal baldness face a lot of ridicule too. You can use hair loss solution to stop hair loss. There are lots of hair loss remedies available in market. Researches have been conducted for future hair loss treatments by lots of companies and they are coming with hair loss discoveries and hair loss products.
Scientists have done a lot of research on hair loss solution, therapies and techniques to over come the problem of baldness. They are still working hard to find more advanced and effective therapies to stop hair loss. A
Finasteride- It’s Use For Hair Loss 2007-09-24 13:24:50 Merck developed this drug in 1992 for the treatment of an enlarged prostate gland. As with Minoxidil, some patients taking Finasteride grew hair on their head. Soon afterwards, it was released as a prescription medication for hair loss treatment.
The main cause of hair loss is DHT (dihydrotestosterone). Finasteride works by stopping the conversion of testosterone to DHT, reducing DHT levels by up to 75%.
The well-known Finasteride product is Propecia. In a study, over 80% of the balding individuals who used it experienced rejuvenated growth, and about 5% commented that their improvement was dramatic.
As well as increasing the number of hairs, Propecia increases the shaft diameter of existing hairs. Most of the improvement, taking Finasteride, will come in the first year of use. Since the main purpose of this drug is to prevent further hair loss, I usually suggest it as a first-line treatment for younger patients, for whom maintaining the hair they have is of prime importance.
The studi Read more:Hair Loss
Advair Diskus: A Brief Overview On This Drug 2007-09-24 13:22:28 What is Advair Diskus?
Advair Diskus is an oral inhaler.
It contains two types of asthma medications. One, to reduce the inflammation of the lungs. The other, to open up the airways.
It is not a direct medication for blood pressure as such. But it has something important to do with your high blood pressure. Even in asthma, it has no power to end a sudden attack. There are other medications available for that.
How should you use Advair Diskus?
The medication is used twice a day, once in the morning and once in the evening. To reduce the risk of possible infections, rinse thoroughly after each take.
What side effects may occur while using Advair Diskus?
It is this issue that needs to be taken care of.
Side effects can not be exact, nor will they inform you in advance. If you feel anything abnormal, please consult your doctor and ask him/her if it would be advisable for you to continue with the treatment.
The side effects reported by people taking Advair are close companions of the other Read more:Brief
, Overview
How DHT Inhibitors Can Stop The Cause Of Hair Loss And Help Promote Hair Regrowth 2007-09-21 13:33:22 For many people who are losing their hair for one reason or another it is important for them to find a way to stop the hair loss and help with hair re-growth. There is something known as DHT inhibitors that can help with the hair re-growth in men and women. DHT is also known as dyhdrotestosterone which causes the hair lose. You will need to find the best DHT inhibitors for you because some of them may not work for your problem.
The products that you will want to check into are:
One: Finasteride - This product has been FDA approved to help in male hair re-growth. There are many men who are taking this to help them stop their hair loss. You will want to do some research about this to find out all you can. You may also want to talk to your family doctor or a dermatologist about this. They will be able to tell you whether it would be the right thing for you to use for your hair loss problem.
Two: Saw palmetto - This is a DHT inhibitor that is not as popular as some of the others. You will Read more:Cause
, Hair Loss
, Promote
Stop DHT with Dutasteride 2007-09-21 13:32:01 Testosterone, a male hormone, is converted into DHT or Dihydrotestosterone in various tissues of human body and the skin. The enzyme 5 alpha reductase converts testosterone into its more potent form DHT. Baldness is largely the result of various hormones interacting over time with those hair follicles that are vulnerable to their effects. DHT is primarily responsible for causing hair loss known as Androgenetic Alopecia in men and women. Whilst there are many other causes of hair loss the primary reason is still DHT!
For men experiencing thinning hair their follicles on the top of the head are genetically vulnerable to baldness. Over time, the hormone DHT acts upon these genetically vulnerable follicles. This hormone binds with the receptor sites of these vulnerable follicles and causes a miniaturization of the hair shaft and follicle over time. The process of hair loss gradually breaks down the follicles’ ability to grow healthy, thick hair.
DTH can be slowed or even stopped by
Advancement in Hair Transplantation 2007-09-21 13:30:49 A standard hair transplantation procedure involves the removal of donor strip of hair from the back of the head from where the follicular unit grafts are dissected under a microscope. These grafts are then preserved in saline and are then transplanted on a bald patch on the crown area of the scalp.
Given the time consuming and tedious nature of this procedure, a hair transplant surgeon is often able to transplant only about 500 to 600 follicular unit grafts per day. However, thanks to the recent hair transplant advances, this technique is often replaced by the follicular unit extraction (FUE). The cost per graft of FUE is typically twice the cost of the standard follicular unit hair transplant procedure discussed above but it is comparatively faster and minimally invasive.
Some hair transplant advances
In a typical FUE procedure a small round punch is made in the donor area to directly extract 1, 2, 3 and 4 hair follicular unit grafts. The follicular units extracted using this process
Simple Tips On How To Breathe Easier Using an Asthma Inhaler? 2007-09-21 13:29:47 Many asthmatics around are constantly plagued by the agony and spending lots of money to conventional treatments such using the right asthma inhaler. These millions asthmatics who have to fight to breathe the precious air our Earth can provide, it can be a constraint on everyday life, including physical activity.
Simple
things such as weather or stress can also trigger an attack. Luckily, there are various ways to control your asthma and live a normal life like using an asthma inhaler.
Having not only asthma inhaler, but also the right asthma inhaler can save your life when an attack hits. Here are 2 basic types of inhalers and what they can do for your asthma:
1) What are Bronchodilators?
This type of asthma inhaler includes metered-dosed brands such as albuterol pirbuterol, and advair. When you have an asthma attack, the muscles in your bronchial tubes constrict, making it hard to breathe.
A bronchodilator relaxes the bronchial muscles so they will open back up. An albuterol or pirbu Read more:Inhaler
Propecia - the Queen of Hair Loss Treatment 2007-09-19 15:56:47 Propecia may sound like a fancy girls name but when it comes to dealing with hair loss she is definitely the Queen
of hair restoration medications. Of all the hair loss products on the market there are only two medications that are approved by the US Food & Drug Administration (FDA) as clinically proven to promote hair growth and hair regrowth while reversing baldness.
Finasteride or Propecia is one, and Minoxidil (Rogaine or Foam Rogaine) is the other and these are the only medications that the FDA has approved and only after very extensive clinical trials.
What is Baldness?
Baldness and hair loss is caused by testosterone, and in particular a version of it known as dihydrotestosterone or DHT, the male hormone that makes us look and sound like guys.
The trouble with testosterone and DHT is that after we become adults they start having a very different set of effects on our body.
You may start noticing hair grow out of your nose or out of your ears - why it does that we have no ide Read more:Hair Loss
, Hair Loss Treatment
, Treatment
Male Hair Loss 2007-09-19 15:55:56 Hair loss usually develops gradually and may be patchy or diffuse (all over). The average scalp contains about 100,000 hairs. Baldness typically refers to excessive hair loss from your scalp and can be the result of heredity, certain medications or an underlying medical condition. Baldness or hair loss is typically something need to worry about. Hair loss during adolescence can mean a person’s sick or maybe just not eating right. Some medications or medical treatments, like chemotherapy treatment for cancer, also cause people to lose their hair. Some hair loss sufferers make use of clinically proven treatments such as finasteride and topically applied minoxidil (in solution) in an attempt to prevent further loss and regrow hair. Hormonal problems may cause hair loss. Many women notice hair loss about 3 months after they’ve had a baby. This loss is also related to hormones. During pregnancy, high levels of certain hormones cause the body to keep hair that would normally fall
Advair (SERETIDE) Side Effects 2007-10-17 15:28:16 A prolonged treatment with Advair may result in some of the following severe (but uncommon) side effects:
Closing of the throat
Difficulty breathing
Hives
Swelling of the lips, tongue or face
Numbness, pain or tingling
Irregular heartbeat or chest pain
Unexplained bruising or open sores
Rash
Worsening breathing
If you are experiencing any of these severe symptoms, you should stop taking this medicine at once. Alert your physician as soon as possible. This medicine might also trigger some other less severe, but more common side effects such as:
Dry throat or mouth after use
Hoarseness, cough or sore throat, deepening of voice
Yeast infection in the throat or mouth
Dizziness, nervousness, headache or tremor
Nausea, vomiting or diarrhea
If you experience any of these side effects, you may continue using Advair, but you should alert your personal physician. Other side effects can also occur. You should contact your personal physician as soon as you can if you experience anything both Read more:Effects
, Side Effects
Advair Intake Guidelines 2007-10-17 15:25:59 Advair is an inhalation medicine. You ought to take this drug exactly how your personal doctor has instructed you to. You can also consult the medicine’s label if you want to get further information. If you fail to understand some of the doctor’s instructions (or some of the instructions that are written in the drug’s label), you should contact a pharmacist, a nurse or a doctor and ask them to explain them to you. You should not disobey any of your physician’s instructions regarding how and when you should take this medicine. This medicine is regularly used two times each day.
Store Advair (Seretide) in a cool and dry place, that is away from moisture and heat. Avoid keeping this medicine in the bathroom or anywhere near the kitchen sink. Store this drug in a place that is far from the reach of pets and children in order to avoid unpleasant accidents such as poisoning.
Advair Dosage
Ask your personal physician to calculate the dose of Advair that works best in your case. Every Read more:Guidelines
, Intake
Advair Warnings 2007-10-17 15:24:04 There is a small but important risk of asthma-related deaths on patients who have been treated with Advair. You should discuss with your personal doctor the disadvantages and the advantages of this particular medicine. Certain medical conditions may harmfully react to a treatment with Advair. They are known to include:
A viral, fungal or bacterial infection of any kind
High blood pressure
Have had an allergic reaction to salmeterol or fluticasone
Heart disease
Glaucoma
Epilepsy or any other kind of seizure disorder
Diabetes
Liver disease
Tuberculosis
If you are suffering from any of the medical conditions that have been listed here, you might not be allowed to start taking Advair or you might have to use a smaller dose of this medicine. Your personal physician might want to monitor your treatment with it.
Advair is a category C FDA pregnancy medicine. Therefore, it has not been clearly determined whether a treatment with this medicine during pregnancy could harm a growing fetus or no
ADVAIR (SERETIDE) 2007-10-17 15:22:05
Advair Information
Advair is a popular medicine that is also generically known under the name of Seretide. This medicine is known to prevent the release of several substances that are able to sometimes cause inflammation in the patient’s organism. This medicine can also improve the patient’s breathing and relax his or her airway muscles.
Advair Indications
Advair is usually prescribed in the case of patients who are suffering from asthma, as it is highly efficient in preventing asthma attacks. This medicine is unable to stop an attack that has already been triggered, because its actions are not fast enough. This medicine is also widely prescribed in the treatment of patients who are suffering from COPD (also known as chronic obstructive pulmonary disease, a disorder that is associated with another disease: chronic bronchitis. However, Seretide can also be prescribed to treat or to prevent some other medical conditions that have not been listed here. Ask your personal physician for
Buy Advair Online | Generic Advair 2007-10-17 15:20:39 Information About Advair
Both generic advair and brand ones are available at drug stores. You may also buy advair or order advair online from online pharmacies such as ours where you can get cheap advair.
Treat Asthma with Advair: Asthma is a very serious condition that can prove to be fatal if not treated correctly. Most people just think of asthma as something that requires a simple puffer, they do not realize what it is really like to not be abet o catch your breath or breathe. It is a very scary feeling to have no control over such a basic function f your body, that is why the pharmaceutical industry is always trying to find new and better ways to treat asthma. Advair is one of the most popular forms of asthma medication and for a long time now it has been helping people lead regular lives just like you and me.
There is more than one single medication in Advair, it is actually a combination of salmeterol (Serevent) and fluticasone (Flovent). These work together to give the suffer Read more:Generic
Faster Hair Growth Products 2007-10-17 15:15:30 Hair grows in cycles so that at any one time around 85 to 90 percent of the hair on our head is in the growth phase, known as Anagen, and the other 10 to 15 percent is in the resting phase or Telogen. There are many reasons why hair might stop growing sooner than it should or start to fall out in greater amounts than normal but the two most common types of hair loss or hair thinning that can occur in both men and women are known as Telogen effluvium and Androgenetic alopecia.
Telogen Effluvium is where a large number of hairs are shed during the Telogen phase of the hair growth cycle leading to widespread thinning of the hair. This can happen at any time in someone’s life and can be triggered by physical or emotional stress or medication or hormonal influences.
Androgenetic alopecia is related to hormone levels in the body and can be hereditary. It is the main cause of baldness in men and although it can affect women too, the pattern of baldness is different. In women it tends to Read more:Growth
, Products
Dutasteride:Treatments That Offer Hope To Hair Loss Sufferers 2007-10-17 15:13:52 Many people experiencing premature hair loss simply resign themselves to a process that is as inevitable as growing old. This is a positive and healthy reaction to what is a natural process for many. But for others the onset of premature balding or excessive hair loss represents a traumatic development that causes untold worry and suffering. This too is a legitimate reaction regardless of whether the hair loss is caused by hereditary factors or some other more complex cause.
Should these sufferers just grin and bear it? No, they should not because there are a number of potentially effective treatments they could utilize, depending on the nature of their hair loss. In this article I will outline some of the most popular hair loss treatments currently available in order to reinforce the fact that hair loss can be treated. The next article in the series will look closely at the treatment regimes best suited to specific ailments such as alopecia areata and telogen effluvium.
At present onl Read more:Hair Loss
, Offer
Effective Hair Loss Baldness Treatment Options 2007-10-17 15:12:06 Hair loss is a very common occurrence, with more than 60 million Americans suffering from it. Since baldness is inherited, a lot of people think that there is no hair loss baldness treatment available for them. The good news is that there are several ways that deal with hair loss problems.
There is a hair loss baldness treatment available for different people. However, the first step in dealing with hair loss is to consult with a doctor and to get a complete medical examination. This is one way of knowing the precise cause of hair loss and determining the best hair loss baldness treatment. Hair loss in men and women can be due to heredity, illness, malnutrition and side effects from medications. The only way to know the cause of baldness for every individual is to consult with a physician.
Hereditary baldness is a condition that medical practitioners don’t have the capability to treat yet. But there have been hair loss baldness treatment options available in the market that can deal Read more:Options
, Treatment
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