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Obesity Doesn't Always Equal Diabetes 2007-09-10 23:59:00 Obesity doesn't mean a person is destined to develop diabetes, experiments in mice suggest. Instead, it may all depend on where the fat is stored.Mice that overate and were very obese still didn't become diabetic, because the activity of two hormones let them store extra calories in fat tissue rather than in their livers or heart muscle."What this mouse model shows is what we have appreciated clinically for a while," said lead researcher Philipp Scherer, a professor of internal medicine and director of the Touchstone Center for Diabetes
Research at the University of Texas Southwestern Medical Center at Dallas."Basically, it shows that for individuals who have the ability to expand their adipose [fat] tissue mass appropriately for the number of calories they take up, those individuals fare much better than someone who has a more reduced capacity to expand their adipose tissue," Scherer said.If fat isn't stored in the adipose tissue, it ends up in the liver and muscles. That, in turn, Read more:Equal
Heart Attack Boosts Diabetes Risk 2007-09-10 23:54:00 After a heart attack, the risk of developing diabetes and so-called pre-diabetes rises steeply, a new study finds.In fact, recent heart attack patients are up to four-and-a-half times more likely to develop diabetes compared with the general population and more than 15 times more likely to develop high blood sugar, according to the report in the Aug. 25 issue of The Lancet."Having a heart attack means that the chances of getting diabetes later are increased," said Dr. Lionel Opie, director of the Hatter Cardiovascular Research Institute at the University of Cape Town, South Africa, and author of an accompanying journal editorial. "We already know that diabetes predisposes one to heart attack, now we add that heart attacks predispose one to diabetes -- one nasty disease leads to another, and it's a two-way process."In the study, a team led by Dr. Roberto Marchioli, from the Laboratory of Clinical Epidemiology of Cardiovascular Disease, Consorzio Mario Negri Sud, Chieti, Italy, collecte Read more:Heart
, Diabetes
Blood Sugar Control Boosts Diabetics' Recovery After Surgery 2007-04-10 09:20:00 It lowers risks for serious infection, study finds, even though we already knew this was the case.Good blood sugar control before surgery reduces the risk of postoperative infections in people with diabetes, U.S. researchers report.The study included 490 diabetic patients, average age 71, who had major noncardiac surgery. Their hemoglobin (Hb A1c) levels were measured within 180 days before the surgery. Hb A1c reflects the patient's control of blood glucose levels during the previous two to three months. Good blood sugar control was defined as an Hb A1c level of less than 7 percent, the American Diabetes Association target.Of the patients in the study, 197 (40 percent) had good blood sugar control, report researchers at Yale University School of Medicine. Patients who did not have good blood sugar control had higher rates of postoperative infections, such as pneumonia, wound infection, urinary tract infection and sepsis (systemic blood infection).Postoperative infections were also mor Read more:Blood
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, Diabetics
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Blood Sugar Control Boosts Diabetics' Recovery After Surgery 2007-04-10 09:20:00 It lowers risks for serious infection, study finds, even though we already knew this was the case.Good blood sugar control before surgery reduces the risk of postoperative infections in people with diabetes, U.S. researchers report.The study included 490 diabetic patients, average age 71, who had major noncardiac surgery. Their hemoglobin (Hb A1c) levels were measured within 180 days before the surgery. Hb A1c reflects the patient's control of blood glucose levels during the previous two to three months. Good blood sugar control was defined as an Hb A1c level of less than 7 percent, the American Diabetes Association target.Of the patients in the study, 197 (40 percent) had good blood sugar control, report researchers at Yale University School of Medicine. Patients who did not have good blood sugar control had higher rates of postoperative infections, such as pneumonia, wound infection, urinary tract infection and sepsis (systemic blood infection).Postoperative infections were also mor Read more:Blood
, Control
, Sugar
, Surgery
, Diabetics
, Recovery
Gene Protects Against Diabetes, Heart Disease 2007-04-10 09:19:00 Why some people no matter what they do will probably never get Type 2 diabetes.People lucky enough to carry a variant in a single gene get added protection against both type 2 diabetes and heart disease, a new study finds.Individuals with the trait aren't immune from the conditions, researchers say, but a study of nearly 7,900 subjects found that they are as much as 48 percent less likely to suffer from either illness."This gives us insight into how heart disease and diabetes may develop," said co-author Eric Rimm, an associate professor of epidemiology and nutrition at the Harvard School of Public Health in Boston.Scientists don't think diabetes and heart disease are inherited, but genes can play a major role, they say. "We do know there are genes that make people more susceptible to becoming diabetic if they're exposed to the right environmental factors," Rimm said. Specific genes have also been linked to heart disease.In mice, a gene variation appears to provide protection agains Read more:Heart
, Diabetes
Oral-lyn Results for Type 1s 2007-04-10 09:18:00 Three-month results of a long-term six-month clinical trial performed in 24 adolescents and 5 young adult patients with type-1 diabetes mellitus (DM) using Oral-lyn, the buccal insulin. This data continuously showed that replacing just 1 one daily subcutaneous injection (s.c.) of regular insulin with Generex Oral-lyn™ during the day, improves parameters of metabolic control in the same manner observed with intensively monitored standard therapy.At the 3rd month evaluation of this six-month trial, it was demonstrated that a trend similar towards normalization exists when replacing the lunch-time dose of regular insulin with the Generex Oral-lyn™ spray. In fact, not only Daily Glucose Profiles and Fructosamine demonstrated improved values but, of special importance, Glycosylated Hemoglobin (HbA1c), the criterion standard to evaluate metabolic control in Diabetes, showed a significant improvement when compared to standard therapy. The investigators concluded, in their three-month inte
Diabetes Drug Use by Children Doubled in US Over 3-Year Period 2007-04-10 09:14:00 Between 2002 to 2005, the use of agents to prevent or treat type 2 diabetes among US children, 5 to 19 years of age, increased from about 0.3 to 0.6 per 1000, which could have "enormous implications" for long-term healthcare needs and expenses, new research shows.Dr. Emily Cox, Express Scripts senior director of research, and colleagues based their conclusions on an analysis of prescription claims for millions of children enrolled with Express Scripts, a St. Louis-based pharmacy benefit management company. This is the first national study to distinguish between the use of agents for type 1 and type 2 diabetes."This study is the first of its kind nationally to reveal the long-suspected national increase in the prevalence of children with or at risk for diabetes," lead author Dr. Cox said in a statement.The largest increase in the use of type 2 antidiabetic agents -- 106% -- was for children between 10 and 14 years of age. The highest prevalence was among 15- to 19-year-old adolescents i Read more:Children
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New oral diabetes drug gets FDA approval 2007-04-10 09:04:00 Diabetics gained a new way of controlling their blood sugar levels Tuesday with the federal approval of a novel pill for Type 2 diabetes, which affects about 20 million Americans.The Food and Drug Administration said it approved Januvia, which enhances the body’s own ability to lower blood sugar levels, after clinical trials showing the new pill works just as well as older diabetes drugs, but with fewer side effects like weight gain. The drug is made by Merck and Co. Inc.The new drug’s cost may limit its use, however. Merck did not immediately disclose what it would charge for Januvia, but it is expected to cost between $3 and $6 a day. Older diabetes drugs can cost 50 cents a day.
Coffee may help prevent diabetes 2007-04-10 09:03:00 Coffee drinkers have a substantially lower risk of developing type 2 diabetes than people who abstain from the beverage, a new study shows. Read more:Coffee
, prevent
Coffee may help prevent diabetes 2007-04-10 09:03:00 Coffee drinkers have a substantially lower risk of developing type 2 diabetes than people who abstain from the beverage, a new study shows. Read more:Coffee
, prevent
Update: 230 millions diabetics in 2025 !! 2007-04-10 08:58:00 More than 230 million people worldwide have diabetes, up from just 30 million in 1985, according to the International Diabetes Federation. Diabetes is expected to affect 350 million people by 2025. Read more:Update
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Diabetics is expected to hit 100 million in 2025 ! 2007-04-10 08:53:00 “There is more diabetes than AIDS. It will take over as the main health problem of the developing world soon,” said Dr Shirine Boardman, a diabetes expert at WarwickHospital in England.In the Western Pacific, a region stretching from Mongolia and Japan in the north to New Zealand in the south, the number of diabetics is expected to hit 100 million
in 2025 from 67million today. Read more:Diabetics
Diabetics is expected to hit 100 million in 2025 ! 2007-04-10 08:53:00 “There is more diabetes than AIDS. It will take over as the main health problem of the developing world soon,” said Dr Shirine Boardman, a diabetes expert at WarwickHospital in England.In the Western Pacific, a region stretching from Mongolia and Japan in the north to New Zealand in the south, the number of diabetics is expected to hit 100 million
in 2025 from 67million today. Read more:Diabetics
DIABETES IS AN EPIDEMIC IN THE 21ST CENTURY! 2007-04-10 00:35:00 In a generation, diabetes has had a six-fold increase. In 1985 there were an estimated 30 million people with diabetes. Today diabetes affects more than 230 million people, almost 6% of the world's adult population. The number of people living with diabetes is expected to grow to 350 million in less than 20 years if action IS NOT TAKEN.
Diabetes in America only: 50 Million by the year 2005 !! 2007-04-10 00:25:00 Every 21 seconds another America
n is diagnosed with diabetes. It affects the lives of 20.8 million children and adults in this country and could rise to 50 million by the year 2025. It’s a tragedy that doesn’t have to happen. With hard work and leadership from Congress, we can end the diabetes epidemic in America. Read more:Diabetes
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