In partnership with Genome Canada, Industry Canada and the Province of Alberta, Genome Alberta is Canada’s newest Regional Genome Centre. In addition to their participation in national genomics programs, they are focused on genomics as one of the central components of the Life Sciences Initiative in Alberta. Their growing strengths in genomics research and technology, centered at [...]
A US-Russian team of scientists claims that they have reconstructed about two-thirds of the genome of the woolly mammoth using DNA extracted from balls of hair. Now, they hopes that it could provide better insights into the extinction of the mammoth and could also lead to resurrection of long-dead species."One can imagine a new field of ‘museomics’ using the collected samples that are now stor
US scientists have mapped the complete genome of a middle-aged female cancer patient who died of acute myelogenous leukemia; they decoded 3 billion bits of her DNA and identified the genes involved in her disease, including 8 new ones.
More: continued here
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Although great strides have been made in gene therapy in a relatively short time, its potential usefulness has been limited by lack of scientific data concerning the multitude of functions that genes control in the human body. For instance, it is now known that the vast majority of genetic material does not store information for the creation of proteins, but rather is involved in the control and r
Although great strides have been made in gene therapy in a relatively short time, its potential usefulness has been limited by lack of scientific data concerning the multitude of functions that genes control in the human body. For instance, it is now known that the vast majority of genetic material does not store information for the creation of proteins, but rather is involved in the control and r
Complete Genomics emerged from stealth mode today brandishing an audacious service model for wholesale next-generation sequencing, with its first human genome already assembled and the CEO’s pledge to reach the magical “$1000 genome” price point as early as spring 2009.Based in Mountain View, Calif., Complete Genomics has raised $46 million in three rounds of financing since its incorporatio
Starting next spring, a complete human-genome sequence can be ordered for $5,000 through a new service announced by Mountain View, California startup Complete Genomics. This stunning price drop (sequencing currently costs about 20 times that amount) could completely change the way that human genomics research is done, and open up new possibilities in personalized medicine.
A $5,000 genome would en
California company Complete Genomics promises in the first half of next year to begin decoding the full genetic sequences at a price of just $ 5,000 for all of about 3 billion nucleotide pairs of the human genome. It is about 20 times cheaper than the current cost, 50-70 times less than the price offered to end-users and 100 thousand times less than the price of the first composite genome decoded
Number of new genetic companies scan the genome of anyone who desires for about $1,000, and communicate information of interest to the customer. This may be information relating to his ancestry, the data on the health status or genetic predisposition to a disease, and much more. The customer can compare their genome with the genome of a celebrity or relatives and friends. Despite the impressive re
I am off to HGM2008 HUGO's 13th Human Genome MeetingHyderabad, India Sat 27-Tue 30 Sep 2008 Hope to meet many of you there and BioSaga will be back in action form OctoberBe a part of the XTractor community. XTractor is the first of its kind - Literature alert service, that provides manually curated and annotated sentences for the Keywords of user preference. XTractor maps the extracted en
Well it so exiting to watch how man makes his future ... The future, always so clear..., had become like a black highway at night. We were in uncharted territory now, making up history as we went along. The future is not set, because we control what happens through the choices we make. The GATTACA era is not far off.23andMe has dramatically slashed the price for its service and expanded its offeri
A study published in the Journal of the American Medical Association said individual human genomes change throughout a person's life influenced by environmental or nutritional factors that may explain why illnesses such as cancer come with age. Such changes could also be hereditary that might explain why some families are more affected by certain diseases than others are.
Researchers at Johns
Comentaba en un post anterior el colapso, la emergencia contínua de herramientas destinadas al microblogging, lifestreaming y redes sociales. Es difícil ya que a estas alturas, alguna de ellas motive la escritura de un post. No lo hicieron ni Jaiku, ni Pownce, ni en los últimos días Plurk (a pesar de ser la más “cool”) [...]
Viruses come in all shapes and sizes. From the very small, such as the picornaviruses or the parvoviruses, to the very large like mimivirus, or the herpesviruses, and poxviruses. These large viruses are not just large in physical size, but in the size of their genomes as well.At the recent 2008 ASM General Meeting, Roger Hendrix of the University of Pittsburgh, laid forth a rather interesting hypo
what is the dna of the our faith? what defines us, moves us, embraces us, motivates us and keeps us? how can we as a collective share voices, ideas and expressions of our faith in a unique and dymanic way? how can we, as followers in the 21st centry, tell the story of our walk, and truly hear all voices? well, i am not sure i have all the answers - ok, i am sure i do not have all the answers
Unlike placental mammals and marsupials the platypus (Ornithorhynchus anatinus) along with several species of echidnas (Family Tachyglossidae) are mammals that lay eggs. They share other characteristics with placental mammals and marsupials like being warm-blooded, having hair and producing milk amongst other characteristics.Aside from laying eggs, the platypus has several other odd characteristics. It has a duck like bill or snout that is used for feeding and feeling about its aquatic habitat. Also, the male platypus has spurs that produce venom therefore making it one of the few venomous mammals along with some shrews and solenodons that can deliver venom. As a side note, solenodons are very odd mammals too and are very rare. Apparently, the oddities of the platypus continue much de
The human body is a marvelous wonder indeed. Scientists still spend countless numbers of hours trying to research our inner workings only to discover pieces of our complex puzzle. The moment we are conceived, our cells are given a blueprint for the building and maintaining of an adult human being. This cellular buildup and maintenance [...]
According to Heather Havenstein of Computer World:
The government-funded effort costs about $20 million a year, the NCI said.
To date, 42 of the institute’s 63 national cancer centers are either linked to the caBIG grid or are installing the necessary infrastructure to participate. Many are already building applications that can be shared by members of the grid.
She [...]
Now there is a new version from the Gnome released. Genome is a desktop environment for Linux users. The new version 2.22 brings some small and new features. The windows manager Metacity is now able to show 3D effects. There is also a Live-CD available to have a look at it. Of course for free!
Imagine: Your body is made of lego blocks.You were put together according to a lego instruction book. The instruction book is very long and complicated. It has 46 chapters. Each chapter has many paragraphs.You have a friend who is also made of lego blocks. He was put together according to an instruction book that is nearly the same as yours, but not quite. It has 46 chapters like yours, but a few of the paragraphs are different to yours.Now imagine there are 8 billion people made of lego blocks, and nearly all of them have the same instruction book, with slight variations.This shared instruction book is the human genome. Other living species, such as animals, plants and bacteria have genomes too, but these are different to the human genome. For example, they usually have a different numb
We’re all swamped with information: emails, documents, pictures and the hundreds of websites we visit every week. There are two ways to deal with the data overload: Get organised and file everything in its right pace. Or you can use GNOME Do, a desktop launcher for Ubuntu in the style of Launchy for Windows and Katapult for KDE, which acts as your humble servant and finds exactly what you’re looking for when you’re looking for it. Sounds too good to be true? GNOME Do is still in the early stages of development but is already showing signs of becoming a desktop essential. Using GNOME Do is simple enough. Use the meta key (usually the Windows key on most keyboards) and the spacebar to bring the search box to the front, then type in what it is you’re looking for. Looking for a directo
The holiday season is here. Are you trying to think of what to get that special someone? Well in the spirit of giving, I shall give a suggestion. For that special scientist in your life, or maybe just science nerd, you can give the gift of knowledge. Knowledge of his or her personal genome, that is.
A company now offers to sequence DNA commercially. Just collect some saliva and mail ship it to them. Oh, and don’t forget your $999 check.
Yup, for less than a grand, a DNA sequence can be bought!
Brave new world.
Oh, I almost forgot. You’ll want the link to the company’s website, right?
It’s 23andMe.com
Sources: New York Times
Photo: Scientists Complete Genome Sequence of Fungus Responsible … - CNNMoney.com
Photo: Scientists Complete Genome Sequence of Fungus Responsible…CNNMoney.com -9 hours agoDespite the role of Malassezia in these and other common skindiseases, including eczema, atopic dermatitis and psoriasis, little was known about the fungus…
Baxter Kidney Patient Education Program Celebrates Tenth Anniversary - CNNMoney.com
Baxter Kidney Patient Education Program Celebrates Tenth AnniversaryCNNMoney.com -18 hours ago…of complex medicalconditions, including hemophilia, immune disorders, cancer, infectiousdiseases, kidneydisease, trauma and otherconditions.…
Guardian Announces Landmark Joint Development Agreement with … - Business Wire (press release)
Guardian Announces Landmark Joint Development Agreement with…Business Wire (press release), CA -15 hours agoEnhanced with Signature Mapping , these systems can detectdis
Science DailyScientists at the University of Florida have identified genetic activity in sharks required for the development of hands, feet, fingers and toes in limbed animals. The finding shows what was thought to be a relatively recent evolutionary innovation existed eons earlier than previously believed, potentially providing insight for scientists seeking ways to cure human birth defects. Sharks (like this Great White off the coast of Guadalupe Island, Mexico) have the recipe for fingers in their genetic cookbook, researchers have found. (Credit: iStockphoto/Keith Flood) When the first four-legged animals sprouted fingers and toes, they took an ancient genetic recipe and simply extended the cooking time, say University of Florida scientists writing in Wednesday's issue of the journal PLoS One. Even sharks -- which have existed for more than half a billion years -- have the recipe for fingers in their genetic cookbook -- not to eat them, but to grow them. While studying the m
Is there one species on earth that is as diverse as the dog? Look at pet cats; they come in more or less the same size and shape. The same is true for sheep, goats and cows. But then consider these AMAZING DOGS. From little Chihuahua’s to giant Great Dane’s, from Hairless Chinese Crested to Afghan Hounds with their luxuriant fur and from cute Toy Poodles to fierce American Pit Bull Terriers. Dogs exhibit the greatest diversity in body size of any mammalian species. Dogs are truly wonderful creatures that brighten up our lives.
We distinguish different dog breeds by their appearance and behavior. On the inside these all look the same, metabolism-wise, as all dog breeds can be traced back in time to their ancestor, the wolf.
Currently there seem to be two schools of thought in dog food (at the very least). One says the “every dog its own food” is a marketing trick, whereas the other school claims breed specific dog food, life stage specific dog food and even gene specific do
Genome of DNA Pioneer Is Deciphered - New York TimesExcerpt:"The full genome of James D. Watson, one of the discoverers of the structure of DNA in 1953, has been deciphered, marking what some scientists believe is the gateway to an impending era of personalized genomic medicine. A copy of his genome, recorded on a pair of DVDs, is to be presented to Dr. Watson today in a ceremony in Houston by Richard Gibbs, director of the Human Genome Sequencing Center at the Baylor College of Medicine, and by Jonathan Rothberg, founder of the company 454 Life Sciences."http://www.nytimes.com/2007/05/31/science/31cnd-gene.html?_r=1&oref=sloginAlex
From the journal Developmental Biology: Free online access to Volume 300 Issue 1, Sea Urchin Genome: Implications and Highlights up until end of June for non-subscribers.
From Eric Davidson's* introductory paper "Special issue: The sea urchin genome":
The Strongylocentrotus purpuratus Genome Project focused the attention of the sea urchin research community as nothing had ever done before. Two numbers tell the story. The first is the more than 9700 genes annotated by volunteers from this research community, guided by the energetic leadership of Erica Sodergren and George Weinstock at the Baylor College of Medicine Human Genome Sequencing Center, where the sequence was obtained and the annotation effort was organized. The second is the number of papers in this very issue, which contains 36 individual studies no one of which could or would have existed absent the genome sequence. Together with the main announcement of the genome sequence in Science and four additional genome-related pap
Excerpts from an open access PLoS Genetics article:SummaryGenome downsizing and fast sequence divergence are frequently observed in bacteria living exclusively within the cells of higher eukaryotes. However, the driving forces and contributions of these processes to the genome diversity of the microorganisms remain poorly understood. The genus Rickettsia, a group of small obligate intracellular pathogens of humans, provides a fascinating model to study the genome downsizing process. In this article, we used seven Rickettsia genomes to reconstruct the genome of their ancestor and inferred the origin and fate of the genes found in today's species. We identify the process of gene loss as the main cause of genome diversification within the genus and show that the rate of gene loss, sequence divergence, and genome rearrangements are highly variable across the various Rickettsia lineages. This heterogeneity likely reflects the intricate effects of specialization to distinct arthropod hosts
News Report from Berkeley Lab's Genomics Division, California: The veil of mystery surrounding our extinct hominid cousins, the Neanderthals, has been at least partially lifted to reveal surprising results. Scientists with the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and the Joint Genome Institute (JGI) have sequenced genomic DNA from fossilized Neanderthal bones. Their results show that the genomes of modern humans and Neanderthals are at least 99.5% identical, but despite this genetic similarity, and that the two species cohabitated the same geographic region for thousands of years, there is no evidence of any significant crossbreeding between the two. Based on these early results, Homo sapiens and Homo neanderthalensis last shared a common ancestor approximately 700,000 years ago.In a paper published in the November 17, 2006 issue of the journal Science, a team of researchers led by Edward Rubin (info), director of both JGI and Berkeley Lab
Global Survey of the Consequences of small and large DNA variants in our Genome:Findings published February 9 2007 in Science (see below) will accelerate the search for genes involved in human disease. The report provides a first genome-wide view of how the unique composition of genetic variation within each of us leads to unique patterns of gene activity.By defining those genetic variants with a biological effect, the results will help to prioritise regions of the genome that are investigated for association with disease. This is an important step to understanding links between genes and disease for individuals, and across populations.The Human Genome Project gave us the instruction manual for building a human. The HapMap and Copy Number Variation (CNV) Projects developed indices of where to find differences in the manuals of different people. One of the challenges for research into variation and disease is that most variants have no consequence for our wellbeing.The new study gives a
